2017 in nearly upon us, but the Heit lab was able to squeeze out one last paper in 2016. This is an exciting moment for our lab, as this study was the major focus of our work for nearly five years. Our goal in this study was to understand how macrophages decide how to respond to the different types […]
Rab17 and Antigen Fate Read More »
The Heit lab is excited to announce our latest publication titled Quantitative Efferocytosis Assays, and published in Methods in Molecular Biology [Pubmed] [Article]. This paper describes many of the microscopy and cell based methods we use to study efferocytosis – the processes by which cells such as macrophages identify, engage, engulf and destroy dying (apoptotic) cells. Efferocytosis plays a key
Efferocytosis Assays Read More »
Yesterday Dr. Roger Y. Tsein of the University of Californian, San Diego, passed away. Dr. Tsein’s work has had a profound impact on the work performed in the Heit lab. Indeed, over half of the experiments we conduct would not have been possible without his discovery and development of fluorescent proteins such as GFP. In our
Today, PLoS Computational Biology has published our study, in which we developed a series of analytical routines for the analysis of molecular interactions in super-resolution microscopy images. These analyses include methods to quantify intermolecular interactions and the formation of larger molecular complexes. This was a large project, involving collaborations across multiple faculties at Western University.
Super-Resolution Imaging Paper Published Read More »
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