Phagocyte Biology Laboratory

Dr. Bryan Heit, Western University


This page hosts our MIiSR Super-Resolution Image Analysis Package. This package allows for the quantification of intermolecular interactions and the formation of higher-order molecular structures in super-resolution microscopy images. Full details of this software’s functionality and use can be found in its attendant paper. If you use MIiSR please cite the following paper:

Caetano FA, Dirk BS, Tam JHK, Cavanagh PC, Goiko M, Ferguson SSG, Pasternak SH, Dikeakos JD, de Bruyn JR and Heit B. (2015) MIiSR: Molecular Interactions in Super-Resolution Imaging Enables the Analysis of Protein Interactions, Dynamics and Formation of Multi-protein Structures. PLoS Comput Biol 11(12): e1004634. doi:10.1371/journal.pcbi.1004634

MIiSR requires Mathworks Matlab 2010a or newer with the image processing, parallel computing and statistics toolboxes.

MIiSR is open source software distributed under a GNU General Public License.

MIiSR Downloads

Version 1.0.0 –¬†Original version, as published in PLoS Computational Biology.

Version 1.0.1 – Corrects an issue which occurs if a file has molecules located at x = 0 and y = o coordinates. Fix changes fileConv.m only.