Tracking Cellular Signaling by Fluorescence Microscopy
In this video the activity of a signaling pathway regulating efferocytosis – the engulfment and destruction of apoptotic (dying) cells by phagocytes such as macrophages – is monitored by fluorescent microscopy. These macrophages are expressing synthetic genes which mark the plasma membrane of the cell in red (PM-RFP), and the signaling lipid PI(3)P in green […]
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