macrophage

Efferocytosis Assays

The Heit lab is excited to announce our latest publication titled Quantitative Efferocytosis Assays, and published in Methods in Molecular Biology [Pubmed] [Article]. This paper describes many of the microscopy and cell based methods we use to study efferocytosis – the processes by which cells such as macrophages identify, engage, engulf and destroy dying (apoptotic) cells. Efferocytosis plays a key […]

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Cages – a New Plasma Membrane Structure

The Heit lab is excited to announce the discovery of membrane cages, a previously undescribed membrane structure. This discovery has been published in the journal Scientific Reports. Membrane cages act to transiently block the diffusion of membrane proteins, thus structuring proteins in cellular membranes over short periods of time. This discovery was made, with our collaborator Dr John de

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Staphylococcus aureus pathogensis review published today!

  The Heit lab, along with our collaborators in the Heinrichs lab, have just published an extensive review of the mechanisms by which the bacterial pathogen Staphylococcus aureus evades killing in the macrophage phagosome. Flannagan RS, Heit B and Heinrichs DE. Antimicrobial Mechanisms of Macrophages and the Immune Evasion Strategies of Staphylococcus aureus. Pathogens. 2015,

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