In the Heit lab we utilise a large range of quantitative image analysis techniques, using a variety of image processing programs. These techniques are used to extract information on protein interactions, cell morphology, cell signalling pathway activity, cell behaviours, and many other aspects of cell activity. Not only do we utilise these tools, but we also develop new […]
Image Processing Resources Read More »
2017 in nearly upon us, but the Heit lab was able to squeeze out one last paper in 2016. This is an exciting moment for our lab, as this study was the major focus of our work for nearly five years. Our goal in this study was to understand how macrophages decide how to respond to the different types
Rab17 and Antigen Fate Read More »
We are excited to announce the publication of a collaborative study, investigating one mechanism which is used by HIV to evade the immune system. This study, a product of our long-standing collaboration with Jimmy Dikeako’s lab at Western University, discovered that the HIV protein Nef sequesters a key component of the immune system (MHC I) inside the cell. MHC
The Heit lab is excited to announce our latest publication titled Quantitative Efferocytosis Assays, and published in Methods in Molecular Biology [Pubmed] [Article]. This paper describes many of the microscopy and cell based methods we use to study efferocytosis – the processes by which cells such as macrophages identify, engage, engulf and destroy dying (apoptotic) cells. Efferocytosis plays a key
Efferocytosis Assays Read More »
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