We are happy to have published two new papers with our collaborators over the past two weeks. The first paper was published with our collaborators Dr. Warren Lee and Dr. Greg Fairn, both from the St. Michael’s Hospital in Toronto, where we identified the mechanisms mediating the transport of HDL (good cholesterol) into the brain. Unlike […]
We are excited to announce the publication of a follow-up paper to last-years study of Rab17 mediate sorting of antigens. In our first study we identified Rab17 as a protein which allowed macrophages to prevent generating immune responses after engulfing dead cells (a process termed efferocytosis), while still allowing macrophages to generate immune responses after engulfing pathogens.
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The Heit lab is excited to announce the publication of our most recent study, which uses evolution as a tool to investigate the biology of the receptor MERTK. Every day the normal turnover of cells in our tissues results in the production of around 100 billion dying cells. These dying cells must be removed to
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2017 in nearly upon us, but the Heit lab was able to squeeze out one last paper in 2016. This is an exciting moment for our lab, as this study was the major focus of our work for nearly five years. Our goal in this study was to understand how macrophages decide how to respond to the different types
Rab17 and Antigen Fate Read More »
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